By Ph.D. Vauthier Denis J. p. Labarre;Gilles Ponchel;Christine
This may be the 5th identify within the new "ULLA" sequence - a sequence of cutting edge introductory textbooks for college kids in pharmaceutical sciences. this article offers a complete evaluation of polymer chemistry study and improvement in pharmaceutics giving insights and up to date details into the explanation in the back of using such molecules, their physicochemical features, man made routes, and sensible examples of formula layout utilizing those components. it truly is a necessary analyzing for any aspiring researcher during this region forming a valid starting place from which to construct on.
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Additional info for Biomedical and Pharmaceutical Polymers (Ulla Pharmacy)
6. 6 Scheme of a capillary viscometer and principle of determination of the intrinsic viscosity of polymers. Biomedical and Pharmaceutical Polymers Chapter No. 2 Dated: 21/9/2010 At Time: 10:12:48 30 | Biomedical and Pharmaceutical Polymers given by the capillary viscometer, a graph giving the reduced viscosity as the function of polymer concentration can be drawn, as shown in this figure. The usually expected straight line is extrapolated back to zero polymer concentration in order to obtain the intrinsic viscosity of the polymer dissolved in this solvent.
2 Dated: 21/9/2010 At Time: 10:12:48 24 | Biomedical and Pharmaceutical Polymers columns are kept in the same solvent during their whole life. This often suggests that one chromatographic setup is reserved for one type of polymer analysis. The more common solvents used are tetrahydrofuran (THF), dimethylsulfoxide (DMSO), chloroform and water. These solvents are chosen from among those that dissolve a large range of polymers. The use of a combination of three detection methods at the outlet of the chromatographic columns allows the determination of the molecular weight of a polymer without the need for calibration of the SEC columns.
However, some hydrogels contain less water, as shown in the case of poly(2-hydroxyethylmethacrylate) (PHEMA). Thanks to the presence of the polymeric network, the internal viscosity of hydrogels is high, resulting in structural strength, decreased resistance to sliding, and decreased permeability to large molecules, making their retention possible. The main characteristic of the liquid phase is that it is not able to flow, because it is trapped in the channels formed by the polymer chains. However, this liquid can be used to dissolve components in the gel, or it can be used for chemical reactions.
Biomedical and Pharmaceutical Polymers (Ulla Pharmacy) by Ph.D. Vauthier Denis J. p. Labarre;Gilles Ponchel;Christine